HistoSonics

HistoSonics was cofounded by University of Michigan engineers and physicians to commercialize histotripsy developed there. Its cofounders include Zhen Xu.⁠[1]

Edison uses focused ultrasound to create bubbles that mechanically destroy targeted liver tumors. The company states that FDA has not evaluated cancer treatment outcomes, five-year survival, or overall survival.⁠[2]

The company website lists Mike Blue as president and chief executive officer.⁠[3]

FDA granted Edison System’s De Novo request DEN220087 on this date, classifying it as a focused ultrasound system for nonthermal mechanical tissue ablation.⁠[4]

The company announced a management-led majority stake acquisition involving K5 Global, Bezos ExpeditionsBezos ExpeditionsBezos Expeditions is Jeff Bezos’s personal investment platform, whose public portfolio spans the internet, enterprise software, life sciences, artificial intelligence, and robotics. Its investment activity is separate from Amazon’s corporate investments, and disclosed holdings include Business Insider, Skild AI, and Generalist.Open the full entry, Wellington Management and others, valuing it at approximately $2.25 billion.⁠[5]

The company announced a $250 million financing led by its new ownership group, with Thiel Bio and Founders FundFounders FundFounders Fund is a venture capital firm founded in San Francisco in 2005 by Peter Thiel and his former PayPal colleagues Ken Howery and Luke Nosek. Run by partners who were entrepreneurs themselves, it argues that founders should keep more control and is known for betting on difficult technology projects in areas such as space, defense, and artificial intelligence. It was Palantir’s first institutional investor, has invested in SpaceX many times since 2008, and its other notable investments include Facebook, Airbnb, Stripe, and Anduril; as of March 2026 it had raised nine early-stage funds and four growth funds.Open the full entry among participants, to support commercial expansion and new clinical applications.⁠[6]

The company announced a De Novo submission to FDA for kidney tumor destruction, explicitly describing that use as investigational at the time.⁠[7]

The company announced financing involving Yosemite and others at a $3.75 billion valuation; the amount raised was not disclosed.⁠[8]

The company announced Edison’s CE mark and a phased European rollout.⁠[9]

The company announced an expanded histotripsy training center at Gleneagles Hospital Hong Kong, increasing hands-on training and clinical observation capacity. The center was established in May 2025.⁠[10]

HistoSonics: Official link: https://histosonics.com/ (opens in a new window)⁠[2]

X: Public account: https://x.com/histosonics (opens in a new window)⁠[11]

LinkedInLinkedInLinkedIn is a social networking platform for professionals. It was founded in 2002 by Reid Hoffman and others, launched in 2003, and listed on the New York Stock Exchange in 2011; after Microsoft acquired it for approximately $26.2 billion in 2016, it became a wholly owned Microsoft subsidiary. Its revenue comes from membership subscriptions, advertising, and recruitment solutions.Open the full entry: Public profile: https://www.linkedin.com/company/histosonics-inc-/ (opens in a new window)⁠[12]