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Sol Chen

Sol Chen is an entrepreneur and a co-founder of Clara Health, a platform that connects patients with clinical trials; she left Brown UniversityBrown UniversityBrown University is a private nonprofit research university in Providence, Rhode Island, and a member of the Ivy League. Chartered by Rhode Island's colonial legislature in 1764, it is known for its undergraduate Open Curriculum, which has no common required core. Christina H. Paxson, president since July 2012, announced on August 3, 2026, that the 2026–27 academic year would be her last in office. As of October 1, 2026, the search for Brown's 20th president remained underway.Open the full entry to start the company, became a Thiel Fellow in 2017, and Clara Health was acquired by M&B Sciences in 2022.

Contents13 sections
Key facts

Early Years: Brown University and Research

She studied at Brown University. Built In Boston’s 2017 article says she was earning a bachelor’s degree in computer science and mathematics there; OneSchema’s 2025 team introduction says she studied computer science, mathematics and economics at Brown University and left to start Clara Health.⁠[1][2]

Founding Clara Health with Evan Ehrenberg

While walking across the Brown University campus she saw, on a telephone pole, a flyer seeking breast cancer patients for a clinical trial, which led her to want an online alternative. She says she discovered the problem “by total accident.”⁠[1][3][4]

M&B Sciences’ press release announcing its acquisition of Clara Health says that Evan Ehrenberg and Sol Chen co-founded Clara Health in 2015 and that the company was created from a collaboration with patient advocates; Built In Boston writes that by 2016 she and co-founder Evan Ehrenberg had formed Clara Health. BIOS Community’s 2020 founder spotlight says that she started Clara Health and that Evan Ehrenberg joined afterwards; it records that Ehrenberg graduated from the University of California, BerkeleyUniversity of California, BerkeleyThe University of California, Berkeley (UC Berkeley) is a campus of the University of California system; the University of California was founded in 1868 through a merger of two institutions and moved to Berkeley, California, in 1873.Open the full entry at 14, began a PhD in computational neuroscience at the Massachusetts Institute of Technology, and took a leave of absence to work at PalantirPalantirPalantir is a U.S. enterprise software company founded in 2003 that provides data and artificial intelligence platforms including Gotham, Foundry, Palantir Apollo, and AIP, serving government and commercial organizations. The company went public through a direct listing in 2020 and now trades on Nasdaq under the ticker PLTR.Open the full entry as a product manager.⁠[5][1][3]

The Massachusetts Biotechnology Council (MassBio) wrote in 2017 that Clara Health was formerly called Xperii. Profiles In Entrepreneurship’s 2019 profile says that she and her co-founder came from regulated technology industries; that in its first year the company was funded mainly by free money from accelerators and pitch competitions, with its first checks coming from the student-founder funds Rough Draft Ventures and Dorm Room Fund; and that the company, then based in Boston, began fundraising there, but the founders felt that investors there were in general overly focused on intellectual-property differentiation and short-term exits; widening their outreach, they found Silicon Valley investors more aligned with their vision.⁠[6][4]

MassBio’s MassCONNECT Mentorship Program

In the summer of 2016 she and Evan Ehrenberg went through MassCONNECT, which MassBio describes as its two-month mentorship program matching entrepreneurs with seasoned life sciences professionals.⁠[6]

Selected as a Thiel Fellow

On June 16, 2017 the Thiel Foundation named the 25 members of the 2017 class of Thiel Fellows, and she was among them. The announcement states that the two-year Thiel FellowshipThiel FellowshipThe Thiel Fellowship is a two-year grant program started by investor Peter Thiel and run by the Thiel Foundation that funds young people who skip or stop out of college to build new things instead. The program has been criticized by figures in education for encouraging young people to leave college.Open the full entry provides young entrepreneurs with $100,000 and mentorship from the Thiel Foundation’s network of technology entrepreneurs, and that the fellows were selected from thousands of applications from around the world. The list gives her as from Cambridge, MassachusettsMassachusettsMassachusetts (officially the Commonwealth of Massachusetts) is a state in the New England region of the northeastern United States; its capital and largest city is Boston. One of the original 13 states, it ratified the U.S. Constitution on February 6, 1788, the sixth state to do so. Its population in the 2020 census (April 1, 2020) was 7,029,917.Open the full entry, with the project “Clara” in the field “Health Technology,” and describes her: “Sol founded Clara, which is building a platform to support patients throughout the clinical trial process, from identification to enrollment and beyond.”⁠[7][7]

BIOS Community’s spotlight says she took the Thiel Fellowship to start Clara Health; the Profiles In Entrepreneurship profile and OneSchema’s team introduction also describe her as a Thiel Fellow.⁠[3][4][2]

Forbes 2018 “30 Under 30” Healthcare List

In November 2017 she and Evan Ehrenberg, as co-founders of Clara Health, were named to ForbesForbesForbes is an American business media brand that began with Forbes magazine, founded by B.C. Forbes in 1917. It is known for rankings such as the Forbes 400, the World’s Billionaires list and 30 Under 30, and operates Forbes.com, ForbesLive events and licensed editions in 81 countries. Since 2014 a majority stake has been held by the Hong Kong investment group Integrated Whale Media; a 2021 plan to list on the New York Stock Exchange through a special purpose acquisition company was terminated in 2022. It is headquartered in Jersey City, New Jersey.Open the full entry’ 2018 “30 Under 30” Healthcare list. Forbes’ write-up says that one of the biggest costs in drug development is finding patients for clinical trials and that Sol Chen and Evan Ehrenberg’s Clara Health is working to streamline the process, “like a Match.com for patients and experimental treatments.” MassBio wrote that they were two of the three MassCONNECT graduates on that year’s list.⁠[8][6][1]

Clara Health’s Platform and Industry Award Shortlists

Built In Boston wrote in December 2017 that Clara Health is a centralized online platform, free for patients, that houses every current study in the United StatesUnited StatesThe United States is a federal country in North America made up of 50 states, the District of Columbia as the seat of government, and territories such as Puerto Rico and Guam; its capital is Washington, D.C. The Continental Congress adopted the Declaration of Independence on July 4, 1776. The 2020 census (April 1, 2020) counted a resident population of 331,449,281, and the 435 seats of the House of Representatives are apportioned among the states on the basis of the census.Open the full entry and abroad; after a match, the company offers “white-glove service,” including guides on stress, trial payments, insurance and travel, and it also helps researchers at hospitals, universities and pharmaceutical companies recruit patients. The article says that Clara Health, still in its first year of operation, had been named a finalist for the SCOPE Patient Engagement Award and Fierce Pharma’s Digital Health Innovation Awards.⁠[1]

Clara Health’s Backers and Business Model

On Choosing Investors and the Company’s Direction

In June 2019 a Profiles In Entrepreneurship profile described her as co-founder and president of Clara Health. She set out three criteria for choosing investors: understanding of and conviction about the market, a similar vision for the company and entrepreneurial empathy from prior operator or founder experience, and concrete added value both immediately and in the long term. The profile says that Clara Health’s long-term aim was to move from an information-aggregator model to a managed-marketplace model. She sees the main value of AI in healthcare as augmenting rather than replacing physicians, “making every 5 minutes of a physician’s time count for 500.”⁠[4]

$11 Million Round Led by Founders Fund and World Without COVID

In April 2020 Clara Health, then based in San Francisco, announced an $11 million round led by Founders FundFounders FundFounders Fund is a venture capital firm founded in San Francisco in 2005 by Peter Thiel and his former PayPal colleagues Ken Howery and Luke Nosek. Run by partners who were entrepreneurs themselves, it argues that founders should keep more control and is known for betting on difficult technology projects in areas such as space, defense, and artificial intelligence. It was Palantir’s first institutional investor, has invested in SpaceX many times since 2008, and its other notable investments include Facebook, Airbnb, Stripe, and Anduril; as of March 2026 it had raised nine early-stage funds and four growth funds.Open the full entry and launched World Without COVID, a free public health initiative connecting people with COVID-19 clinical trials, including vaccine, treatment, antibody testing and blood plasma transfusion studies; its database listed more than 300 COVID-19 trials, automatically updated every day from data pulled from clinicaltrials.gov and other sources. Evan Ehrenberg was then co-founder and chief executive; Drug Discovery and Development writes that Clara Health’s investors included Khosla Ventures and Founders Fund and that it had patient and medical support from people at institutions including UCSF, Takeda and the Massachusetts Institute of Technology.⁠[10][11]

Clara Health Acquired by M&B Sciences

M&B Sciences, which describes itself as a fast-growing, technology-driven and African-American-owned clinical research organization, announced in a release datelined San Diego, CaliforniaCaliforniaCalifornia is a U.S. state on the Pacific coast; its capital is Sacramento and its largest city is Los Angeles. California was admitted to the Union on September 9, 1850, as the 31st state. Its population at the 2020 Census (April 1, 2020) was 39,538,223, the largest of any state.Open the full entry, that it had completed the acquisition of San Francisco-based Clara Health on March 1, 2022, with financial terms not disclosed; the combined company would operate as M&B Sciences and planned to integrate Clara Health’s Clara Platform with the NeighborhoodTrials platform. The release says that Clara Health had served more than thirty biotech and pharmaceutical clients and that its platform had expanded to protocol design, site selection and retention.⁠[5]

On OneSchema’s Operations Team

On January 27, 2025 OneSchema, a company that automates the ingestion, normalization and validation of client data, published a team introduction by its co-founder and chief executive Andrew Luo that lists her under Operations, noting that she had received the Forbes 30 Under 30 award and the Thiel Fellowship and that Clara Health had been backed by Founders Fund, Khosla Ventures and top angel investors.⁠[2]

Related Organizations, Websites, and Public Accounts

Thiel Fellowship: Official website: https://thielfellowship.org/ (opens in a new window).⁠[12]

Sources12 sources

  1. This Boston startup wants to connect patients to clinical trials faster than ever (opens in a new window)builtinboston.com↑
  2. Introducing the OneSchema team (opens in a new window)oneschema.co↑
  3. Founder Spotlight #7: Evan & Sol @ Clara Health (opens in a new window)medium.com↑
  4. Sol Chen, co-founder of Clara Health, on building transformative healthcare companies (opens in a new window)medium.com↑
  5. M&B Sciences Inc Acquires Clara Health and Announces Goal to Become a Leader in Patient Recruitment and Retention in Clinical Trials (opens in a new window)businesswire.com↑
  6. Three MassCONNECT Grads Make Forbes 30 Under 30 List (opens in a new window)massbio.org↑
  7. Thiel Foundation Announces 2017 Thiel Fellows (opens in a new window)marketscreener.com↑
  8. Clara Health (opens in a new window)forbes.com↑
  9. Alumna’s company connects patients with clinical trials (opens in a new window)news.northeastern.edu↑
  10. Clara Health Raises $11M to Launch COVID-19 Clinical Trial Initiative (opens in a new window)builtinsf.com↑
  11. Clara Health, tech leaders form COVID-19 clinical trial initiative (opens in a new window)drugdiscoverytrends.com↑
  12. Thiel Fellowship (opens in a new window)thielfellowship.org↑