Biohub

Chan Zuckerberg Biohub received a $600 million commitment and brought together UC Berkeley, UCSF and Stanford. Its initial projects covered cell atlases and infectious diseases.⁠[1]

The Chicago Biohub was announced with the University of Chicago, Northwestern and the University of Illinois Urbana-Champaign. Led by Shana O. Kelley, it focused on tissue measurement technologies and inflammation.⁠[2]

The New York Biohub brought together Columbia, Rockefeller and YaleYale UniversityYale University is a research university in New Haven, Connecticut. Its predecessor, the Collegiate School, received a charter in 1701. Trustees chose New Haven in 1716; the institution became Yale College in 1718 and Yale University in 1887. Yale provides undergraduate, graduate and professional education and has 14 undergraduate residential colleges. As of October 2026, its president was Maurie McInnis, who took office in July 2024. In 2026, Yale expanded aid for incoming undergraduates and celebrated its 325th anniversary.Open the full entry under Andrea Califano, aiming to engineer immune cells for research into early disease detection.⁠[3]

Scientific teams were united as Biohub and the EvolutionaryScale team joined; Alex Rives became head of science.⁠[4]

Biohub announced a five-year, $500 million commitment: $100 million for external research and $400 million for internal technology and data generation, aiming to build open biological data.⁠[5]

The organization released ESMC, ESMFold2 and ESM Atlas for protein representation, structure prediction and data exploration. The reported binder validation was conducted in laboratory experiments.⁠[6]

Biohub and Berkeley researchers reported improved cryo-EM contrast for small proteins using a laser phase plate. Biohub’s dual-laser system was described in a preprint.⁠[7]

Biohub announced expanded cooperation with the U.S. Department of Energy, NIH and others, totaling $1.8 billion in funding, data and computation, including data resources built through previous federal investment.⁠[8]

Biohub operates through entities including Chan Zuckerberg Biohub, Inc., with strategic, funding and operational support from CZI.⁠[9]

Alex Rives leads science; Scott Fraser, Shana O. Kelley and Andrea Califano head the San Francisco, Chicago and New York teams, respectively.⁠[10]

CELL×GENE supports exploration of single-cell data; the CryoET Data Portal enables open sharing of cryo-electron tomography data.⁠[11]

Biohub Platform provides protein models, the Fold structure-prediction tool, ESM Atlas and developer documentation.⁠[12]

The organization encourages researchers to post preprints before peer review to accelerate the exchange of findings.⁠[13]

Its investigator program supports interdisciplinary collaboration; affiliated investigators receive flexible support to explore new tools and techniques.⁠[14]

Biohub: Official website: https://biohub.org/ (opens in a new window)⁠[15]

Chan Zuckerberg Initiative: Official website: https://chanzuckerberg.com/ (opens in a new window)⁠[16]

Biohub Platform: Official website: https://biohub.ai/ (opens in a new window)⁠[12]

University of California, Berkeley: Official website: https://www.berkeley.edu/ (opens in a new window)⁠[1]

University of California, San Francisco: Official website: https://www.ucsf.edu/ (opens in a new window)⁠[1]

Stanford University: Official website: https://www.stanford.edu/ (opens in a new window)⁠[1]

The University of Chicago: Official website: https://www.uchicago.edu/ (opens in a new window)⁠[2]

Northwestern University: Official website: https://www.northwestern.edu/ (opens in a new window)⁠[2]

University of Illinois Urbana-Champaign: Official website: https://illinois.edu/ (opens in a new window)⁠[2]

Columbia UniversityColumbia UniversityColumbia University, formally Columbia University in the City of New York, is a private research university in New York City and a member of the Ivy League. Founded in 1754 by royal charter from King George II as King's College, it is the oldest institution of higher education in New York State and the fifth oldest in the United States. It was renamed Columbia College in 1784 and adopted the university name and moved to Manhattan's Morningside Heights in 1896. It has 17 schools and four affiliated colleges, with 35,978 students enrolled in fall 2025. Legal scholar Jennifer L. Mnookin became president on July 1, 2026.Open the full entry: Official website: https://www.columbia.edu/ (opens in a new window)⁠[3]

The Rockefeller UniversityThe Rockefeller UniversityThe Rockefeller University is a biomedical research university on Manhattan’s Upper East Side in New York City, devoted mainly to scientific research and graduate education; it grew out of the Rockefeller Institute for Medical Research founded by John D. Rockefeller.Open the full entry: Official website: https://www.rockefeller.edu/ (opens in a new window)⁠[3]

Yale University: Official website: https://www.yale.edu/ (opens in a new window)⁠[3]

U.S. Department of Energy: Official website: https://www.energy.gov/ (opens in a new window)⁠[8]

National Institutes of Health: Official website: https://www.nih.gov/ (opens in a new window)⁠[8]

EvolutionaryScale: Official website: https://www.evolutionaryscale.ai/ (opens in a new window)⁠[17]

Public X Account: Official account: https://x.com/biohub (opens in a new window)⁠[18]

Public LinkedInLinkedInLinkedIn is a social networking platform for professionals. It was founded in 2002 by Reid Hoffman and others, launched in 2003, and listed on the New York Stock Exchange in 2011; after Microsoft acquired it for approximately $26.2 billion in 2016, it became a wholly owned Microsoft subsidiary. Its revenue comes from membership subscriptions, advertising, and recruitment solutions.Open the full entry Account: Official account: https://www.linkedin.com/company/cz-biohub/ (opens in a new window)⁠[15]

Public YouTubeYouTubeYouTube is Google’s video-sharing and creator platform, founded in 2005 by Steve Chen, Chad Hurley, and Jawed Karim and acquired by Google in 2006. Built around video uploading, viewing, and creator earnings, the platform has developed Shorts, YouTube Music, Premium, YouTube TV, and products for children, and is headquartered in San Bruno, California, United States.Open the full entry Account: Official account: https://www.youtube.com/@officialbiohub (opens in a new window)⁠[19]

Public Facebook Account: Official account: https://www.facebook.com/biohub/ (opens in a new window)⁠[15]

Public Instagram Account: Official account: https://www.instagram.com/biohub/ (opens in a new window)⁠[15]

Public Threads Account: Official account: https://www.threads.com/biohub/ (opens in a new window)⁠[15]

Public Bluesky Account: Official account: https://bsky.app/profile/biohub.org (opens in a new window)⁠[15]